| Year | FILM – Actors | Rank | Wks | Adjusted Gross |
| 1931 | CIMARRON Richard Dix, Irene Dunne | 1 | 3 | $66,930,000 |
| 1931 | THE GREAT LOVER Adolphe Menjou, Irene Dunne | 6 | $10,140,000 | |
| 1932 | SYMPHONY OF SIX MILLION Ricardo Cortez, Irene Dunne | 4 | $28,640,000 | |
| 1932 | BACK STREET Irene Dunne, John Boles | 2 | $57,670,000 | |
| 1933 | NO OTHER WOMAN Irene Dunne, Charles Bickford | 10 | $16,950,000 | |
| 1933 | THE SECRET OF MADAME BLANCHE Irene Dunne, Lionel Atwill | 5 | $27,700,000 | |
| 1933 | THE SILVER CORD Irene Dunne, Joel McCrea | 1 | 1 | $26,470,000 |
| 1933 | ANN VICKERS Irene Dunne, Walter Huston | 2 | $36,610,000 | |
| 1933 | IF I WERE FREE Irene Dunne, Clive Brook | 5 | $24,500,000 | |
| 1934 | THIS MAN IS MINE Irene Dunne, Constance Cummings | 4 | $33,020,000 | |
| 1934 | STINGAREE Irene Dunne, Richard Dix | 2 | $28,510,000 | |
| 1934 | THE AGE OF INNOCENCE Irene Dunne, John Boles | 5 | $30,160,000 | |
| 1934 | SWEET ADELINE Irene Dunne, Donald Woods | 5 | $17,190,000 | |
| 1935 | ROBERTA Irene Dunne, Fred Astaire | 1 | 4 | $105,750,000 |
| 1935 | MAGNIFICENT OBSESSION Irene Dunne, Robert Taylor | 1 | 2 | $83,690,000 |
| 1936 | SHOW BOAT Irene Dunne, Allan Jones | 1 | 2 | $103,800,000 |
| 1936 | THEODORA GOES WILD Irene Dunne, Melvyn Douglas | 1 | 1 | $76,120,000 |
| 1937 | HIGH, WIDE AND HANDSOME Irene Dunne, Randolph Scott | 5 | $45,800,000 | |
| 1937 | THE AWFUL TRUTH Irene Dunne, Cary Grant | 1 | 2 | $105,880,000 |
| 1938 | JOY OF LIVING Irene Dunne, Douglas Fairbanks Jr. | 4 | $56,550,000 | |
| 1939 | LOVE AFFAIR Irene Dunne, Charles Boyer | 1 | 2 | $73,340,000 |
| 1939 | INVITATION TO HAPPINESS Irene Dunne, Fred MacMurray | 1 | 1 | $42,270,000 |
| 1939 | WHEN TOMORROW COMES Irene Dunne, Charles Boyer | 3 | $53,740,000 | |
| 1940 | MY FAVORITE WIFE Irene Dunne, Cary Grant | 1 | 2 | $93,710,000 |
| 1941 | PENNY SERENADE Cary Grant, Irene Dunne | 2 | $124,560,000 | |
| 1941 | UNFINISHED BUSINESS Irene Dunne, Robert Montgomery | 5 | $51,240,000 | |
| 1942 | LADY IN A JAM Irene Dunne, Patric Knowles | 10 | $42,230,000 | |
| 1943 | A GUY NAMED JOE Spencer Tracy, Irene Dunne | 1 | 1 | $246,080,000 |
| 1944 | THE WHITE CLIFFS OF DOVER Irene Dunne, Alan Marshal | 1 | 4 | $218,700,000 |
| 1944 | TOGETHER AGAIN Irene Dunne, Charles Boyer | 2 | $129,750,000 | |
| 1945 | OVER 21 Irene Dunne, Alexander Knox | 4 | $113,690,000 | |
| 1946 | ANNA AND THE KING OF SIAM Irene Dunne, Rex Harrison | 1 | 2 | $173,000,000 |
| 1947 | LIFE WITH FATHER William Powell, Irene Dunne | 1 | 3 | $249,960,000 |
| 1948 | I REMEMBER MAMA Irene Dunne, Barbara Bel Geddes | 1 | 3 | $129,750,000 |
| 1950 | NEVER A DULL MOMENT Irene Dunne, Fred MacMurray | 6 | $53,590,000 | |
| 1950 | THE MUDLARK Irene Dunne, Alec Guinness | 9 | $37,610,000 |
NUMBER ONE BOX OFFICE HITS: 15
TOP TEN BOX OFFICE HITS: 36
TOTAL BOX OFFICE GROSS: $2,815,300,000 (Adjusted in 2016 USD)
Complete US Box Office Charts (week-by-week)
with grosses are available here:
https://www.amazon.com/Weekly-Grossing-Film-Charts-1930s-ebook/dp/B072K3LTPF/
Box Office Madness 